About NRPP
The NRPP supports Proteome Informatics as well as the development of advanced technologies for interaction maps, phosphoproteomics, quantitative proteomics and organellar proteomics. A major portion of NRPP resources are directed towards development of algorithms and software for protein identification, interaction maps, analysis of post-translational modifications and protein expression profiling. Significant efforts are also put into data standards for developing and testing proteomics algorithms and tools, as well as software and databases for integrating proteomics data.
Core Features of the Resource
- Integration of technologies for analysis of protein function
- Development and refinement of technologies for phosphoproteomics, quantitative proteomics, and pathway mapping
- Large scale subcloning and yeast two-hybrid interaction maps
- Visualization tools for interaction maps (Cytoscape in the Trey Ideker lab and the Protein Interaction Map Browser in the Finley lab)
- Development of Proteome Informatics algorithms and tools to support existing and new proteome technologies
- Standard datasets for interaction maps and mass spectrometry (for evaluation of proteomics software)